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OCR: hesised Renin is a proteolytic enzyme that is sy of the and stored by specialised cells in the wa omerulus afferent arteriole that is situated in the ly and of the kidney. These cells are anatomica he wall of functionally associated with the cells in n the the distal convoluted tubules, which fo known as macula densa, and the whole structure the juxtaglomerular apparatus. inactive Renin is produced in both an active an een used form. Various in vitro techniques have to activate the inactive enzyme, includi treatment with trypsin, pepsin, or acid, ble for in incubation at -4℃. The enzyme respons ne vivo activation of renin is probably a se protease, possibly kallikrein,